One of the host factors recognized by this yeast is hemoglobin, which binds to a specific cell surface receptor.
In this connection, it has been demonstrated that the dauer pheromone binds to a specific cell surface G-protein-coupled receptor (GPCR), resulting in activation of the G-protein α-subunits GPA-2 and GPA-3 (homolog of mammalian G-protein G o) α-2 and α-1, respectively) in amphid neurons (Zwaal et al., 1997).
However more detailed examination has shown that the adult hermaphrodite nematode allows some bacteria to enter the gut and bind to a specific set of cells, the INT9 gut cells.
A general characteristic of the proteins that bind noncovalently to the cell wall is the presence of one or more so-called cell wall-binding domains (CWBDs) that bind to a specific ligand of the cell wall.
These results indicate that a specific chemical structure with the intact triazino[5,6-b]indol-3-ylthio butanoyl]-10H-phenothiazine is crucial for p53 actriazino[5,6-b]indol-3-ylthio butanoyl]-10H-phenothiazine triazino[5,6-b]indol-3-ylthio butanoyl]-10H-phenothiazine
In the testis, osteocalcin can bind to a specific receptor in Leydig cells and enhances testosterone synthesis and, consequently, increases fertility [ 206].
Pheromones released by one type of cell bind to a specific receptor of the other type.
" Lefkowitz's own scientific odyssey began in the early 1970s when he tried to develop a molecule that would bind to a specific receptor on the surface of a cell, which is like making a key for a lock that is too small to see.
In order to trigger a biological response, such signaling molecules must first bind to a specific receptor protein, often located on the cell surface.
Early this year, Dr. Karsenty's team published a study demonstrating that in mice a protein called osteocalcin, which is produced by bone-forming cells called osteoblasts, binds to a specific receptor on cells of the testes.
