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However fragments can exhibit unspecific binding and even if they bind to a specific binding site in some cases more than one binding mode is observed [1].
A general characteristic of the proteins that bind noncovalently to the cell wall is the presence of one or more so-called cell wall-binding domains (CWBDs) that bind to a specific ligand of the cell wall.
Aptamers are single-stranded DNA or RNA molecules that can selectively bind to a specific ligand with high affinity and specificity.
The researchers also pinpointed the precise location on the molecule--called the antigen-binding site--that allows it to bind to a specific foreign molecule or pathogen.
In contrast, using a competitive-binding assay will allow for identifying ligands that bind to a specific site on the target.
Each lymphocyte bears receptors that bind to a specific antigen.
Each snippet will only bind to a specific spot on the DNA molecule.
The method depends on adaptors that bind to a specific sequence of the four DNA letters on the tail of each bead's gene.
The Northwestern researchers have demonstrated that it's possible to create coatings that bind to a specific type of acid important for blood-vessel growth and stem-cell differentiation.
At the core of SHERLOCK's success is a CRISPR-associated protein called Cas13, which can be programmed to bind to a specific piece of RNA.
For instance, one end of the protein might bind to a specific metal particle and the other end might stick to the surface of a semiconductor such as gallium arsenide.
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