Sentence examples for bind to a small from inspiring English sources

Another parameter to consider is the size of the binding pocket at the target receptor; searches are usually performed to find fragments that can bind to a small particular area of the binding site at the target receptor, in that case, a user-defined ligand is needed for that purpose.

This localization is in turn dependent on the Homer family of scaffolding proteins which bind to a small motif on the distal C-termini of mGluR1 and 5, localize the receptors near the PSD, strengthen coupling to post-synaptic effectors and simultaneously uncouple the mGluRs from extra-synaptic effectors such as voltage dependent ion channels.

Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen.

Through their C-terminus, Cullins constitutively bind to a small RING finger protein, either RBX1 or RBX2, which forms the catalytic core of the ligase complex.

AIDA requires a large protein fragment (larger than 30 kDa; in the current case, the p53 protein) to bind to a small protein (less than 20 kDa, here the N-terminal domain of MDM2 of ca. 120 amino acids).

Successful targeting of PPIs is also made possible due to the ability of the small molecules to bind to a small fraction of the residues contributing to the interface, also known as binding hotspots, which contribute the most to the free energy of interaction.

NOX1, 2 and 4 all bind to a smaller p22phox subunit, which is essential for enzyme activity.

The interaction with integrin αvβ6 was still viable however, suggesting that the RGD motif could still bind to a smaller repertoire of integrins.

Analysis of similarity between canonical homeodomain TF binding specificities between fruit fly and mammals using these existing datasets suggested that fruit fly homeodomains bind to a smaller subset of sites than human homeodomains.

The experiments reveal that the MHC class I molecules that can bind to a larger variety of protein fragments (so-called 'generalists') are present in lower numbers on the surface of cells than molecules that can bind to a smaller variety of fragments (so-called 'specialists'specialists

The BMCC1 C-terminal isoform BNIPXL binds to a small GTP-binding protein RhoA and Lbc, a RhoA-specific guanine nucleotide exchange factor (RhoGEF), through its BCH domain, leading to the inhibition of RhoA-dependent stress fiber formation and malignant transformation.