Sentence examples for bind to a site from inspiring English sources
In some cases, the inhibitor can bind to a site other than the binding-site of the usual substrate and exert an allosteric effect to change the shape of the usual binding-site.non-competitive inhibitor binds to a site other than where the substrate binds.
Ligands that bind to a site generally overlap well with binding hot spots (Hall et al. 2012); therefore, on the basis of our results, we are convinced that TPP binds to PPARγ in a manner very similar to the binding of selective partial agonists.
A TF may bind to a site on the DNA but this binding event is not necessarily functional.
These studies, and comparative analyses of the kinetics with thio-NAD+ and quinone electron acceptors, provided evidence that Mtb NDH-2 catalyzes the transfer electrons from NADH to quinone substrates by a nonclassical, two-site ping-pong kinetic mechanism whereby substrate quinones bind to a site that is distinct from the NADH-binding site.
Nicotine is not a competitor nor a substrate for DAT [30], and it does not bind to a site on the DAT protein [31].
Activated Rac1 was found to specifically bind to a site in exon 10 of isoform 2 in vitro.
Crystallographic structures of aminoglycosides bound to A-site systems clarified many static aspects of RNA ligand interactions.
EF-P binds to a site located between the binding site for the peptidyl tRNA (P site) and the exiting tRNA (E site).
It binds to a site that substantially overlaps the IP3-binding site, and structure activity studies with synthetic analogues of AdA have established that the adenine (or another aromatic group) is essential for its enhanced affinity.
Surprisingly, 17B1.3 binds to a site on B7-H6 that is completely distinct from the binding site for NKp30, such that 17B1.3 does not block the NKp30 B7-H6 NKp30 B7-H6.
Indeed, also for TRPC3, 6 and 7, PI 4,5 P2 is bound to a site localized in the C-terminal calmodulin-IP3-receptor-binding site (Patterson et al, 2002; van Rossum et al, 2005; Kwon et al, 2007).
