Hence, FOXM1 also bound to a significant number of unique sites, suggesting that FOXM1 might uniquely control the transcription of specific sets of genes in a manner independent from ERα or that ERα might operate along with FOXM1 present at different sites via looping together of different chromatin locations.
Previous studies suggest that D2Rs interact with arrestins relatively weakly [35] and none of the dopamine receptors are known to bind arrestins to a significant degree in their non-activated state [36], the condition examined in the presence study.
The changes are bound to have a significant effect because "The West Wing," which has won numerous other awards, has always been a product of Mr. Sorkin's personal vision.
When Bertelsmann broke ranks with its fellow music giants and announced its deal with Napster on October 31st, the move confirmed that the Internet is bound to become a significant form of music distribution, and perhaps the main one.
Democrats were bound to lose a significant number of those vulnerable seats during the subsequent midterm cycle, when voters, having had their catharsis, generally feel some buyer's remorse about the incumbent president's party.
In 2016, it launched only eight rockets, versus its projected 20, which is bound to have a significant impact on its revenue for this most recent full calendar year, too.
"The provisional settlement is disappointing news from the Welsh government and bound to have a significant effect on the level of Council Tax and future services.
The NMC Horizon Report: 2014 Higher Education Edition (Johnson et al. 2014) identifies the emerging technologies that are bound to have a significant impact on learning, teaching and creative thinking in higher education.
This is bound to have a significant impact on the risk of hypoglycemia in these patients.
Whereas many causes underlie health disparities, unequal access to healthcare services is bound to explain a significant portion of the observed inequality [ 3].
