Sentence examples for bind to a regulatory from inspiring English sources

A large number of transcription factors (TFs) could simultaneously bind to a regulatory sequence.

The RFX TFs bind to a regulatory motif termed the X-box.

These techniques include chromatin immunoprecipitation (ChIP), which purifies fragments of DNA that bind to a regulatory protein, such as a transcription factor or a covalently modified histone.

31 Sulphonylureas bind to a regulatory subunit of the inward rectifier potassium (KATP) channel, leading to an increase in intracellular potassium ion concentrations, the opening of voltage gated calcium channels, and an influx of calcium ions.

Alternatively, p65 could bind to a regulatory element located far away from the promoter to regulate transcription, as has been shown for several NF-κB target genes [ 20- 22].

Mechanistically, noncompetitive antagonists are considered better suited for a more selective blockade of AMPA receptors, because noncompetitive antagonists bind to a regulatory site(s) distinct to the agonist site and their actions should not depend on the concentration of an agonist.

RA binding to RAR/RXR heterodimers bound to a regulatory DNA element leads to a cascade of events resulting in recruitment of transcriptional co-activators and initiation of transcription [35], [37].

The CFTR ATP-dependent chloride channel is a 1480-residue monomer containing two membrane-spanning domains (MSD1 and MSD2, each with six transmembrane helices) alternating with two cytosolic nucleotide-binding domains, one of which is bound to a regulatory region (NBD1-R and NBD2; Fig. 2) (Mornon et al., 2009).

Different from existing thermodynamic models, STAP explicitly expresses the expected number of TFs bound to a regulatory sequence, and thus it is directly applicable to analyze binding intensities reflected in whole-genome binding data.

The side chain of Lys285, located in the αH-αI Loop of the large lobe, is typically solvent exposed and often disordered in crystal structures where the C-subunit is not bound to a regulatory subunit.

For example, Zc3h8 (also known as fetal liver zinc finger protein 1, Fliz1) directly binds to a regulatory element located within the first intron of GATA-3 gene through its CCCH motifs and strongly represses GATA-3 transcription [19].