Sentence examples for bind to a pocket from inspiring English sources

The seven C-terminal residues bind to a pocket located at the surface of one β monomer.

The inhibitors were shown to bind to a pocket formed after undergoing a conformational change from an open to a closed active site state.

Recent results with the GABA, NMDA and AMPA receptors suggest that ethanol can bind to a pocket in certain subunits, altering the sensitivity of the receptor to its ligand [4].

Here, we describe the structure of CDC25B catalytic domain with two small molecule ligands that bind to a pocket in the vicinity of a protein protein interaction hot-spot.

We were unable to model S20 into the H3 structure; however, HA fusion inhibitors that are specific for group 2 HAs have been reported and are predicted to bind to a pocket near the same loop region in the group 2 HA structure.

Cmpd-15PA binds to a pocket formed primarily by the cytoplasmic ends of transmembrane segments 1, 2, 6 and 7 as well as intracellular loop 1 and helix 8.

A framework of how capsaicin binds and activates TRPV1 has started to merge: capsaicin binds to a pocket formed by the channel's transmembrane segments, where it takes a "tail-up, head-down" configuration.

However, there is evidence that only one polymerase is bound to a pocket at one time, and that this is the active polymerase [20].

Since muscimol binds to a pocket formed by an alpha and a beta GABAA subunit in a multimeric GABAA receptor, any rescue of the Gad1lacZ or ViaatlacZ mutant phenotypes by muscimol would suggest that multimeric GABAA receptors were the downstream target of Gad1 or Viaat function [36], [38], [39], [40].

A common feature of all 3 antibodies is that the hapten binds to a pocket or cleft that is surrounded by a "rim region" of residues without major contribution to hapten binding.

The corresponding structure in the Fold-X dataset is that of a calmodulin of Paramecium tetraurelia 17 (PDB entry 1exr), and the conspicuous affinity value probably refers to an unusual fifth Ca2+-ion bound to a pocket that, according to the crystallographers, probably had been created by crystal contacts and thus may be without functional relevance.