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Mss4/Dss4 proteins are known to bind to a nucleotide-free (GDP/GTP-free) form of small GTPases, the so called Rab proteins.
The rEGSs consisting of the random 14-nucleotide sequence (N14) and a cytosine (C) were designed to bind to a G nucleotide in the target RNA.
They treated the samples with fluorescent probes, molecular tags designed to bind to a particular nucleotide sequence in microbial RNA.
Q96JZ8_Hum (GPR87) is closely related to UDP-glucose receptor (P2YX_Hum) and might bind to a modified nucleotide ligand.
Each zinc finger domain recognizes a 3- to 4-base-pair (bp) DNA sequence, and individual domains can be arranged in tandem to bind to an extended nucleotide sequence that is unique within a genome.
Its SH2 domain docks to specific EGFR phosphotyrosine residues and its SH3 domains bind to a Ras guanine nucleotide exchange factor, Sos [ 8, 9].
Molecules of particular interest for delivery across membranes are drugs and nucleic acids, such as small interfering ribonucleic acids (siRNA), given that this allows the normally inactive siRNA access to bind to a cell's specific nucleotide sequence that performs a given task, such as regulating endogenous genes [ 3].
The seven zinc finger ZNF143 TF has been reported to bind to an ~18-21 ~18-21leotide sequence [ 27, 28].
During the initiation of translation in prokaryotes, the 3′ end of the 16S subunit of the ribosome is known to bind to a short stretch of nucleotides located about 5 7 bases upstream of the start codon.
Experiments reported by Han et al. (2009) utilized murine I642G IRE1, a homolog of L745G yeast IRE1, that binds to a modified nucleotide, 1NM-PP1.
It binds to a guanine nucleotide exchange factor called ECT-2 to switch RhoA on, which in turn promotes the formation of the contractile ring.
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