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When a protein with multiple phosphorylation sites is experimentally profiled with an antibody, which recognizes only a single phosphorylation site, the antibody will actually bind to a heterogeneous mixture of phospho-states provided that the epitope is phosphorylated (e.g., anti-AKTpS473 Ab may bind to both AKTpS473 and AKTpS473_pT308 but not to AKTpT308).
Similar(59)
However, the heterogeneous mixtures of oligomers of varying sizes and conformations formed by Aβ42 have obscured the nature of the oligomeric species that bind to a given receptor.
The ability to bind to heterogeneous peptide sequences in this way is not confined to the polymers of α1-antitrypsin induced by loop cleavage but also occurs with the heat-induced oligomers of polymerogenic forms of antithrombin and with mutant Z α1-antitrypsin [25].
Heterogeneous catalysts are usually bound to a polymer support and have the potential to be used in continuous processes.
Gabapentin binds to a channel.
is bound to a non-CML namespace.
Over the years, she has helped to transform the country from a homogeneous, monocultural farming nation, exporting bacon and butter to a heterogeneous, multicultural creative economy driven nation.
We do it to prepare students to become lifelong learners who can navigate in and contribute to a heterogeneous world after graduation.
It is related to a heterogeneous data exploration topic (or heterogeneous data mining).
In contrast, anti-U1-RNP antibodies bind to RNP, a ribonuclease-sensitive antigen involved in splicing heterogeneous nuclear RNA into mRNA.
The last set corresponds to an heterogeneous marginal distribution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com