Sentence examples for bind to a consensus from inspiring English sources

The basic region, which consists of approximately 17 amino acids and is located at the N-terminus of the domain, is a DNA-binding region that allows HLH proteins to bind to a consensus hexanucleotide E-box (CANNTG) [ 5, 6].

Puf3p is also known to bind to a consensus motif in the 3'UTR of many mRNAs encoding mitochondrial proteins [16] [16].

In AngII-infused rats for 3 days, a nuclear blue staining, indicating active Smad complexes that bind to a consensus Smad sequence in DNA, was observed in many vascular cells, while few positive cells were found in control, simvastatin or atorvastatin treated samples (Figure 2C).

Most bHLH factors bind to a consensus sequence that is contained in the promoter region of their target genes.

Both ERβ-503 and ERβ-485 bind to a consensus estrogen response element (ERE) and heterodimerize with each other and with ERβ [ 8, 9].

2) AP-1 transcription factors are leucine zipper proteins that bind to a consensus DNA sequence (5'-TGAG/CTCA-3') as a dimeric complex.

This assay is analogous to the traditional electrophoretic mobility shift assay in that it measures the ability of a transcription factor from nuclear lysates to bind to a consensus-binding sequence of that transcription factor, and has been extensively validated [ 20, 21].

The bcl-2 gene is a direct target of BP1 since: (i) BP1 protein bound to a consensus binding sequence upstream of the bcl-2 promoterter in vitro.

The Fur protein is a homodimer that, upon binding its co-repressor Fe2+, binds to a consensus sequence in the promoter of Fur-regulated genes, repressing their transcription [ 27, 28].

In DNA binding gel shift assays, the in vitro synthesized ER77 binds to a consensus vitellogenin A2 oestrogen-response element.

Nanog-TAT can be readily expressed in and purified from E. coli and binds to a consensus Nanog DNA sequence.