Sentence examples for bind to a common from inspiring English sources

Also, the flexibility of intrinsic disorder helps different disordered regions to bind to a common binding site on a common partner.

We previously suggested that disordered segments with different sequences could use their flexibility to bind to a common binding site, thereby facilitating many-to-one signaling [ 35].

As different from ours, phenytoin inhibited Na+ channels in N4TG1 mouse neuroblastoma cells with an IC50 value comparable to that of lamotrigine [ 21], and phenytoin, lamotrigine, and carbamazepine were suggested to bind to a common binding site of Na+ channels in rat hippocampal CA1 neurons [ 22].

In both cases, previous experimental evidence shows the two partners are not capable of binding each other alone, suggesting that a chaperone is required to enable binding, or that these interactions require both proteins to bind to a common intermediate or complex of intermediates.

Runx2 belongs to the family of Runt-domain transcription factors, which bind to a common partner, CBF β, to form a core binding factor (CBF) complex and can activate or repress gene transcription.

This cross-detection could be abrogated in both tests by adding a blocker (heterologous antigen) to remove the antibodies responsible, which presumably bind to a common antigen (O12) located close to O2 and O9.

It is therefore very likely that OT binds to a common binding site that is located in between those four residues (Arg, Phe, Tyr and Phe) as proposed in the OTR model.

It turns out that a bunch of vastly different countries, each with control over its own budget but all bound to a common currency, is not a sustainable economic model.

Therefore, it appears that although some GO terms were enriched with more than one of the proteins, it is not because these proteins bound to a common set of messages that connects to one particular GO term, but rather that they were associated with different messages that belong to the same functional class.

First, in mutant-expressing cells, two to three lateral kinetochore pairs were bound to a common microtubule fiber.

They consist of three distinct α-subunits (CD11a, CD11b, and CD11c) that are bound to a common β-subunit (CD18).