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In 1994, tomato systemin was found to bind to a 50KDa protein in the cell membrane of tomato.
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The DNA-binding domain can specifically bind to a 17bp recognizing sequence motif (GAL4rec).
MYB46 and MYB83 bind to a 7 bp consensus sequence, termed as SCWs MYB-responsive element (SMRE) to regulate the expression of target genes (Zhong and Ye, 2012).
In addition CPMV is known to bind to a 54 kilodalton mammalian surface protein (CPMV-BP) [42].
Previous studies have shown that ISWI is unable to bind a 15 or 18 bp DNA substrate but is able to bind to a 23 bp DNA substrate.
Up to two Hsp70 subunits can bind to an Hsp40 dimer in this way.
Through its KIR motif, p62 is able to bind to Keap1, a Cullin3-ubiquitin E3 ligase complex adaptor protein.
Although we showed previously that RUNX1 binds to a RUNX1-binding motif ∼1.4kb upstream of the ESR1 transcription start site, this binding is relatively weak (∼3-fold enrichment).
As was stated above, Avd(S16C) efficiently bound to a 2-iminobiotin affinity matrix, which qualitatively suggested relatively high biotin-binding affinity.
There are differences between the structures of human MDM4 domain bound to VH9 and those of human and zebra fish MDM4 bound to a p53 peptide.
Here, we report the crystal structure of VHL bound to a Cul2 N-terminal domain, Elongin B, and Elongin C (EloC).
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