Sentence examples for bind the weak ligand from inspiring English sources

The concentration [P]free of the protein that remains free to bind the weak ligand can be derived from the definition of the dissociation constant KDstrong of the competitor: (7) where b= [P]0+[Lstrong]0+ KDstrong) and [Lstrong]0 is the total concentration of the competitor.

The OXTR has a weak ligand selectivity profile.

It is believed that BMPRII does not actually bind the ligand but rather stabilizes and/or accelerates ligand binding to BMPRI.

Our P-DNA platform enables the control of this process by using two orthogonal surface DNA strands to bind the integrin ligand and a growth factor of interest.

Once the dissociation constant KDweak of the weak spy ligand and its LLS lifetime in the bound form TLLSbound are known, it is possible to optimize [Lstrong]0 and [P]0 to rank strong competitors according to their binding strengths.

Does a strong ligand present at a low concentration outweigh the effect of weak ligands present at high concentrations?

Restoration of the motif in the scavenger D6 confers weak ligand-induced signaling activity [31].

Therefore, at high, but non-saturating, ligand concentrations, greater ligand occupancy at cryocooled temperatures would increase the observable electron density for weak ligands at receptor binding sites.

Three were very weak ligands and the remaining compounds did not bind detectably to NMO antibodies at all when assayed in a microarray format.

Two different BMP receptors are expressed in the limb mesenchyme, BMPR1a (and3) and BMPR1b (ALK6) that bind the different BMP ligands with different affinities.

Of particular interest to us was that the peptoid analogue of 1 lacking a chiral center essentially failed to bind to the anti-ADP3 antibodies and that the enantiomer of 1 was a much weaker ligand.