Sentence examples for bind the same substrate from inspiring English sources

While it was possible to infer the size and some properties that characterize the binding pockets, highly divergent residue arrangements appear to bind the same substrate (Table 2, see Additional file 5).

This interaction was highly specific, because Cdc48 and Ufd1 did not bind the same substrate when it was translated from a message that includes a stop codon.

As noted in the introductory section, a major open question about SH7PC enzymes is how they bind the same substrate and produce different products, with the most conceptually confusing aspect being how EEVS produces one stereochemistry at position C5 of the product (derived from the substrate C2 atom, as shown in Figure 1B) while EVS produces the other.

Only a few of the transporters and regulators in this group bind the same substrates; galactose (MglB and GalR), ribose (RbsR and RbsB) and xylose (XylF and XylR).

The observation that double combinations of neuraminidase inhibitors were not synergistic is consistent with the fact that all three drugs are known to target the same enzyme, and all bind in the same substrate binding pocket in a similar manner [19].

Given that all NAIs bind in the same substrate binding pocket in NA, the use of these drugs in combination in the absence of enhanced activity raises the risk of selecting for a single mutation that could confer resistance to both neuraminidase inhibitors simultaneously.

The co-crystal structure of PAP and TBBPA bound to SULT1E1 reveals TBBPA binding in the same substrate binding pocket as E2.

The proteins that bind to the same substrate-binding site may compete with each other for regulation if they exist in the same cellular compartment.

The superimposed LRP6 c-motif (pink sticks), e-motif (light green sticks) and pS9 auto-inhibitory N-terminal peptide (light blue sticks) bind to the same substrate-binding pocket between the C-loop (yellow) and activation loop (red).

These observations strongly support the contention that all enzymes encoded by the genes included in these analyses bind and utilize the same substrate, phenylalanine.

Both proteins are known to bind partly the same substrates and are both expressed in the brain [19,22,34].