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Additionally, differences in RF-NH2 receptor structures which bind the same peptide explained ligand specificity.
Type A conformers are more stable than type B pMHCII conformers but bind the same peptide in the same register.
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We observed that some PDZ domains share identical subsequences in the 10 and 16 binding positions but bind the same peptides with different affinity.
If the highly similar allelic variants expressed on homologous haplotypes are also able to bind the same peptides, it is very likely those haplotypes would mount similar CD8+ T-cell responses in both Chinese- and Indian-origin rhesus macaques.
Polyclonal antibodies were purified using the same peptide bound to Sulfolink Coupling Gel (Pierce) according to manufacturer's instructions and dialyzed against PBS before storage.
The same peptide construct (covalently bound to Affi-Gel 15 media, Bio-Rad Laboratories, www.bio-rad.com) was used for affinity purification of aHv1-N, after the serum of the immunized rabbit was depleted for anti-glutathion-S-transferase antibodies.
We have previously reported that biotinylated 15d-PGJ2 (15d-PGJ2-bindsnds to H-Ras in vitro and in intact cells at the same peptide [14], [15].
Dieker et al. demonstrated that samples from 26 of 35 patients with SLE bound more strongly to a triacetylated 22-amino acid peptide from histone H4 than to the non-acetylated version of the same peptide [ 21].
The same peptides containing Rme2s or Rme were bound less tightly by approximately 1 kcal/mol, although the host displayed no selectivity against trimethyllysine.
"We were able to take the same peptides that participate in biological processes in our body and to create nano-crystals — these are stable, robust spheres.
ABT-737 is considered to be a Bad-like BH3 mimetic because both ABT-737 and Bad BH3 peptide bind the same subset of Bcl-2 pro-survival proteins [27] and induce cytochrome c release in mitochondria obtained from "primed for death" tumor cells [28].
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