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Despite this interaction, the two proteins avoid any binding overlap on the target mRNAs: AGO proteins preferentially bind the boundaries of UTRs, while ELAVL1/HuR binds uniformly along UTRs and disappears toward the stop codon and the polyadenylation site [ 39].
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The forward primer binds at the boundary of the donor site of the pSPL3 vector and at the beginning of exon 2 of the DSPP gene, while the reverse primer binds at the middle of exon 4 of the DSPP gene.
Mutations in the proteins that bind insulator DNA elements that define the boundaries of chromatin domains can give morphogenetic readouts in Drosophila, as recently reported in BMC Biology by Bonchuk et al. in the Georgiev laboratory.
Together, these two side chains define the boundaries of the pocket that binds and constrains the shape of the nascent base pair: Y766 (blue) on the template side and E710 (yellow) on the dNTP side.
The designer lets loose without the boundaries of shoes and boards to bind him.
There are also bound to be traffic problems near the boundaries of the tolled area as car drivers skirt around its edge to avoid paying the fee.But if the scheme survives the inevitably difficult transition period and the computers don't collapse, the mayor's political prospects do not look bad.
"These were not the boundaries of peace.
They were the boundaries of repeated wars".
The boundaries of additional subdivisions are approximate.
Push the boundaries of taste.
Many test the boundaries of free expression.
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