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This technology provides a relatively rapid means of generating novel antigen-binding molecules that bind strongly to immobilized antigen.
It was found that synthesized compounds, especially compound 6 (evident from binding constant value) bind strongly with calf thymus DNA, presumably via an intercalation mode.
Neither nucleotide nor Mg2+ ions alone bind strongly to PKA, whereas together their binding affinities increase substantially.
The chlorophenoxy herbicides bind strongly to albumin [ 134], and binding is favoured by longer acid chains and by more greatly substituted aromatic rings.
Therefore, while IAA does bind strongly to AFB5, selection for more than a single binding geometry suggests that there might be additional endogenous ligands still to be described.
Chitin-binding reagents such as Alexa488-labeled lectin wheat germ agglutinin (WGA) bind strongly to och1Δ but weakly to the parental strain (Figure 2C).
HOC bind strongly to carbonaceous ENP.
Colloidal particles can bind strongly to fluid interfaces and assemble into thin layers.
After a few repetitions, only the viruses that happen to bind strongly remain.
Paper electrode: Nanotubes absorb into paper and bind strongly to cellulose fibers, as shown in this scanning-electron micrograph.
In particular CDC6 was found to bind strongly to ORC1 and ORC2, and to MCM7 proteins.
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