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A break very close to one end or the other of the target site may create a target that still binds to the probe, though with reduced affinity; a break closer to the middle of the target site may produce fragments that bind partially to the probe, competing for binding with perfect matches.
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However, the later authors isolated a single chain antibody (VHH) that binds partially to the 2F5 epitope, but lacked binding to W66655.
Hg2+ which served as the competitor, binds partially to the capture DNA oligonucleotide signal transducer while the Qdot reporter (MAA-capped CdTe/ZnS) was used as the signal reporter.
NATs can bind partially to mRNAs through base complementarity, and can inhibit transcription or translation by different mechanisms; these include transcriptional interference [ 1], RNA masking [ 2], CpG methylation [ 3], and RNase-H-mediated mechanisms [ 4].
But, when the miRNAs bind partially, the translation of mRNA is repressed.
However, they would not serve their purpose in fulfilling these roles if they would diffuse too far away from the fungus, and maybe due to their chitin-binding properties, they stay partially bound to the cell wall, serving as a reservoir to be partially released under the right growth conditions.
Since FDH stock solution contains 2-mercaptoethanol (ME) for stabilization, ME is partially bound to the Au electrode.
It turns out that TETN partially binds to the IgY14-Supermix resin column [ 25].
21, 22 ZNS is partially bound to the human serum albumin (about 50%) and preferentially accumulated in erythrocytes.
Nevertheless, we cannot rule out that some of the identified proteins may be localized to various compartments: e.g., some secreted proteins, in addition to be soluble outside the cell, are partially bound to the surface by non-covalent interactions.
Thus, many genes that are involved in protein (re)folding are induced to bind to partially unfolded proteins to protect them from degradation or aggregation [ 25].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com