Sentence examples for bind more poorly to from inspiring English sources
Our attempt to deliver cyclic peptides by cFΦR4 by the endocyclic method had only limited success; an increase in cargo size from one to seven residues led to progressively poorer cellular uptake, likely because the larger, more flexible rings bind more poorly to the cell membrane.
If a microtubule under tension is strained so as to make the severing enzyme katanin bind more poorly than to an unstrained microtubule, then severing will prefer MTs that are not aligned to the stress direction, and will eliminate them.
Because 3 is structurally similar to 2 and differs only in the carbonyl O atom on the cyclohexane ring, the additional steric crowding of this oxygen in 3 very likely accounts for why this pterin analogue binds more poorly.
The inability to form direct bifurcated H-bonds with the heme propionate D in eNOS is likely the main reason why (3 R,4 R) - 2 and (3 R,4 R) - 3 bind to eNOS more poorly than to nNOS (Tables 1 and 2).
Transcription factors bind DNA at specific sequence motifs and they bind more strongly to some sites than others.
The rationale behind this step was that ribosome-associated Ub conjugates that remained bound to the ribosome would bind poorly to UBA beads because ribosomes do not efficiently penetrate the pores of a Sepharose resin, whereas Ub conjugates released from the ribosome by puromycin would be able to bind more efficiently to UBA beads.
In Drosophila melanogaster, 4E-BP exhibits a nonconsensus eIF4E-binding site and binds poorly to eIF4E [43].
But if a need for GAG binding by gp70 explained MuHV-4 GAG-dependence, then gp70-deficient MuHV-4 should bind poorly to GAG+ cells, much as the wild-type binds poorly to GAG− cells [6].
This is consistent with the notion that the panel does not have mutations nearby that can challenge these violations, but that these inhibitors could bind poorly to other functional HIV-1 protease variants with more disruptive mutations in the vicinity.
While aminoglycosides bind poorly to proteins, the percentage of echinocandins bound to proteins in serum exceeds 90%.
