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PADs typically exist as homodimeric proteins in solution and, according to crystallographic studies, bind in a head-to-tail fashion.
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The cholates assemble in a head-to-tail fashion to form infinite hydrogen-bonded chains.
SDCS molecules wrap around the AmB in a head-to-tail fashion into a nanomicellar structure.
As a result, they align in a head-to-tail fashion to form long streams.
Microtubules are built of αβ-tubulin heterodimers organized in a head-to-tail fashion.
Several of these basic modules are connected to each other in a head-to-tail fashion.
Homodimeric mammalian TrxR consists of two subunits in a head-to-tail arrangement.
Thus, the three TnPKR genes are tandemly arranged in a head-to-tail orientation.
Tropomyosin (TM) is a dimeric coil-coiled protein that binds along actin microfilaments forming a head-to-tail polymer.
Similar to the ERM family proteins, the CTD of Merlin can directly bind to its FERM domain, thus forming a head-to-tail auto-inhibited conformation.
The former possibility is supported by the structural study demonstrating that Ste50 binds Ste11 in a head to tail fashion [19], which could also explain the ability of Ste50 to form homo-oligomers (Figure 4).
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