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Though highly diverse in sequence, the HIV-1 PR substrates bind in a conserved three-dimensional shape we termed the substrate envelope.
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ORC was initially discovered in the budding yeast Saccharomyces cerevisiae, through its ability to bind to a conserved sequence present in this organism's origins of DNA replication.
In this study, we employed a proteomics-based approach, named RNA-protein interaction detection (RaPID), to comprehensively screen for host proteins that bind to a conserved motif within the rotavirus (RV) 3' terminus.
Finally, residues 399 403 of the PID of ctPan2 bind in a highly conserved groove formed by residues 599 603 and 562 573 in the CTD of chain B of the Pan3 dimer (Fig 6D).
TIPIN (TIMELESS interacting protein) recognizes and binds RPA-coated DNA in a conserved complex with TIMELESS (Gotter, 2003).
Drosophila Polycomb protein (Pc) binds to H3K27me3 through a conserved N-terminal chromodomain16.
These results indicate that CTCF directly binds M1+M2 in a highly conserved manner.
These primer pairs specifically bind to a region conserved in all wPip groups for each gene (Supplementary Table 2).
They bind to a highly conserved region in the HA stem region and share the fusion peptide as a part of their epitopes.
MAb 7B2 binds a well conserved epitope in the helix-loop-helix region of gp41.
However, all share a conserved cytoplasmic tail that binds catenins.
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