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These factors bind cooperatively to the IFN-β enhancer and recruit coactivators and chromatin-remodeling proteins to the IFN-β promoter.
These splice-site elements are initially recognized by U1 snRNP, which binds at the 5' splice site, and by SF1/mBBP, U2AF65 and U2AF35, which bind cooperatively to the branchpoint sequence [3], [4], polypyrimidine tract [5], [6] and 3' splice-site AG dinucleotide [5], [7], [8], [9], respectively.
Furthermore, Mss11p and Flo8p bind cooperatively to the STA1 promoter, leading to the filamentous and invasive growth response [ 31].
During DNA contact, two MYB repeats are closely packed in the major groove, so that the two recognition helices bind cooperatively to the specific DNA recognition sequence motif.
FruA and MrpC2 have been shown to bind cooperatively to the promoter regions of several genes or operons that are important for aggregation and sporulation [ 45– 45].
Also, why do the authors think that the mCrm1 molecules bind cooperatively to the Rev-RRE complex if they don't actually touch one another?
Similar(53)
As cytosolic cAMP concentrations rise, cAMP binds cooperatively to the two regulatory domains of protein kinase A (PKA) causing the release of its two catalytic subunits (Fig. 1d).
A plausible interpretation is that anti-PEG antibodies directed against the backbone of the polymer can bind cooperatively to at least two sites within the backbone of a polymer as large as 10 kDa PEG diol.
It has been shown that Smad4 dimers can bind cooperatively to DNA even in the absence of direct physical contacts [ 30].
Several monomers of DnaA bind cooperatively to oriC and induce DNA melting required for assembly of the replication forks [ 17- 19].
CEH-20 is a member of the conserved Pbx family of transcriptional regulators, initially identified as human leukaemic proto-oncogenes (Laurent et al., 2008), that are known to bind cooperatively to Meis proteins via interaction of their conserved PBC domains with the Meis Homothorax-Meis (HM) domain (Abu-Shaar et al., 1999; Rieckhof et al., 1997; Ryoo et al., 1999; Stevens and Mann, 2007).
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