Sentence examples for bind client from inspiring English sources
This in turn affects the ability of the hetercomplex to bind client kinase proteins in a very precise manner, selectively affecting those that regulate cell motility.
Further work is required to determine the size(s) of the 7B2 species that best bind client proteins.
To aid this process, ER-resident chaperones bind client proteins and promote correct folding by minimizing mis-folding and aggregation in a biologically relevant timescale (2).
CTD1 has a hydrophobic pocket shown to bind client peptides in this class of J-proteins, as well as the zinc finger-like domain extruding from it, which also may be involved in client binding [20 22].
Importantly, the dissociation constants (Kd) obtained for R126W (13.61 ± 2.7 µ m) and P509S (15.72 ± 1.9 µ m) were comparable with the Kd measured for wild-type (15.63 ± 1.4 µ m), suggesting that human PD variants retain the ability to bind client proteins to normal levels (Fig. 1G and Supplementary Material, Table S1).
In the first program in the series, a homeless man describes a rape, a male prostitute details his murder of a wheel-chair bound client.
The PCNA protein contains two interaction domains (not to be confused with the structural domains discussed above); one binds client proteins and the other binds DNA.
The binding of ATP to the N-terminal nucleotide-binding domain of Hsp90 promotes dimerization of the N-termini and clamping around the bound client protein.
The trends in the data are clear – irrespective of CP, the percentage of G. gibberifrons CCT that bound client declined with increasing temperature, whereas the percentage of bovine CCT bound to CP increased.
The monomer ('A' form) at the center of the schema binds clients and is shifted to BiP Substrate complexes by mounting unfolded protein load.
It is also tempting to speculate that GRP78va might act as a cytosolic chaperone collaborating with its cytosolic co-chaperones to promote the folding of nascent cytosolic polypeptides, since it corresponds to the GRP78 mutant initiated from Met-148 in previous study and exhibits strong ATP binding activity [44], implicating that GRP78va has the ability to bind to client proteins.
