Exact(2)
Here, Xist RNA was found to bind broadly across the X chromosome, though enriched at gene-dense sites, in particular at sites of silenced genes.
Siglecs are mainly expressed by cells of the immune system and bind broadly to sialylated structures of the same cell or of neighboring cells through their extracellular domain (Crocker et al., 2007).
Similar(6)
In stark contrast to site-specific targeting factors, KDM2B binds broadly to promoter-associated CpG islands through its nonmethylated DNA-binding activity, occupying genes covering the complete expression spectrum (Farcas et al., 2012; He et al., 2013; Wu et al., 2013).
The results show that HAMLET binds broadly to membranes under physiological conditions, in contrast to HLA.
We performed replicate experiments at soluble competitor concentrations of 0.025x, 0.25x, 2.5x, 5x, and 10x of k252a, a staurosporine analog that binds broadly to protein kinases.
The structures also contain bound broadly neutralizing antibodies as a focus for vaccine design.
The SWI/SNF complex binds broadly to several kilobases around the start site of many genes expressed in ESCs, including Oct4 target genes (Ho et al., 2009; Kidder et al., 2009).
This is the first demonstration of human NoV P domain protein as a functional target for the selection of nucleic acid aptamers that specifically bind and broadly recognize diverse human NoV strains.
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