Sentence examples for bind at the intersubunit from inspiring English sources

MD [19], DNPS and 4-NBT [20] have been proposed to bind at the intersubunit region in PfTrxR's.

The three ATP binding sites are located at the intersubunit interfaces within the trimer, suggesting that ATP binding promotes subunit rearrangement and ion channel opening.

In all complexes the inhibitors bind at a novel allosteric site located at the intersubunit interface, inducing structural changes within FabG incompatible with NADPH binding and catalysis.

The binding cavity is formed within a four-helix bundle structure at the intersubunit interface, with two helices provided by each monomer.

These movements, in combination with head-to-tail arrangement of the helices at the intersubunit interface, lead to the formation of a cavity where the inhibitors bind.

The [4Fe 4S] cluster ligated to three cysteines and one glutamate is encapsulated at the intersubunit interface.

Consistent with such roles, R765 and R444 are located at the intersubunit interface in our fit.

To investigate the usefulness of such a method in the study of AcrB trimer stability, we chose to take advantage of the W13 W895 pair because these amino acids are close to each other at the intersubunit interface.

However, the map showed that there was considerable variability in the conformation of the small ribosomal subunit (40S), the CrPV-IRES (located at the intersubunit space), and the L1-stalk of the large ribosomal subunit.

Because the goal of this study is to investigate how trimer affinity correlates with AcrB efflux activity, we introduced mutations to disrupt protein protein interactions at the intersubunit interface.

The docking results indicate that (S --mecamylamine interactS --mecamylaminevely leS --mecamylaminedinteractsthe intersubunit site located betwith the α4- and β2-TMDs (see the α4/β2-intersubunit site in Table 1).