Sentence examples for bind at the interface from inspiring English sources
Many biochemical studies support the view that the juxtaposed G- and T-segments bind at the interface of the B'/A' DNA binding and cleavage core and the ATPase domains [1].
Benzodiazepines bind at the interface of the α and γ subunits on the GABAA receptor.
FK506 is known to bind at the interface of FKBP12 and calcineurin [27].
Rapa is known to bind at the interface between FKBP12 and TOR, resulting in TOR inhibition [26].
We show that both Mal and TRAM are strongly predicted to bind at the interface of a TLR4 TIR homodimer, a result consistent with multiple other studies using mutagenesis of receptor and adaptor TIRs and blocking peptides.
Both ligands were shown to bind at the interface of two subunits.
This study showed that the receptor binds at the interface of the subunits with three receptor molecules binding to one trimer, with two main sites of interaction on the ligand.
In chain A, the FAD is noncovalently bound at the interface of a Rossman-type domain and the substrate-binding domain.
They share a common structure of two 4 domains linked by a long helix, with the metal bound at the interface between the domains.
It follows that these Arf-GEFs are predicted in vivo targets for the fungal metabolite Brefeldin A (BFA), an established inhibitor of the secretory pathway which binds at the interface between the Sec7 domain and Arf-GDP in vitro [17], [18].
