Sentence examples for bind at the acidic from inspiring English sources
Ruthenium red is widely used as a channel blocker in electrophysiology of sensory neurons, but only just recently has been mapped to bind at the acidic tetrad of TRPV1 (Fig. 10).
As the functionally active ELV motif in VpuCD is a putative acidic dileucine sorting signal, we hypothesized that Vpu binds AP1 at the acidic dileucine-binding site located at the γ and σ1 subunits.
By FACScan analysis, we showed that HB-19/Btn binding to HUVECs is specific since it is prevented by the excess HB-19 but not by the basic 9Arg peptide or the F3 peptide (Figure 3B), which is reported to bind the acidic amino acid region located at the N-terminal part of nucleolin [6].
VpuCD (cyan) binds to the acidic dileucine binding pocket of γ/σ1, and BST2CD (magenta) binds to the tyrosine-binding pocket in μ1.
Histones are highly basic proteins that bind tightly to the acidic DNA to form chromatin.
Ubiquitin E3 ligases RNF168 and BRCA1 exhibit defective ubiquitylation when the acidic patch is mutated and IL-33 binds to the acidic patch, likely in a manner similar to the LANA nucleosome targeting peptide.
The current data point towards a model in which the CRL3KLHL3 complex binds to the acidic degron motif leading to WNK4 ubiquitylation and proteasomal degradation.
In this context, α-glucosidase may start to bind heme just during its release from hemoglobin, during its digestion, avoiding heme precipitation at the acidic pH in the R. prolixus midgut.
The average vagina falls at the acidic end of the pH scale.
