Sentence examples for bind at specific sites from inspiring English sources

TFs are special types of proteins that have DNA binding domains that can bind at specific sites of DNA defined by particular sequences of certain length.

Proteoglycans bind at specific sites along the fibrils [6,7] and play a role in fibril assembly, matrix organisation and ultimately corneal transparency [8].

In this mechanism, the TFs bind at specific sites in the promoter region of a gene using their DNA binding domain and thus affect the expression of the target gene (TG).

Protein complexes bound at specific sites throughout the genome present obstacles to the replication fork (Ivessa et al. 2003).

ERs are able to bind DNA at specific sites in the genome and thereby control gene activity by recruiting transcriptional mediators and co-regulators, as well as a host of other nuclear proteins with different roles in ER-mediated control of gene activity [ 5, 6].

Sry-type high-mobility group box-9 (Sox9) is a regulatory transcription factor that binds DNA at specific sites within Col2a1, Agc1 and Hapln genes to induce their transcription [ 4- 6].

These inhibitors have been developed to covalently bind to cysteines at specific sites of the kinase.

Pioneer factors bind to DNA at specific sites, opening up the chromatin structure in many different contexts (Zaret and Carroll, 2011).

One strand of this duplex is incorporated into RISC (RNA-induced silencing complex), which binds to mRNAs at specific sites with base-pair complementarity to the miRNA; generally these sites are located in the 3′-UTR (untranslated region) of the mRNA [ 9].

PG core proteins such as the small leucine rich repeat proteins (sLRRP) decoron, biglycan and fibromodulin bind to collagen fibrils at specific sites and carry anionic glycosaminoglycan (AGAG) strings which span the interfibrillar spaces [8] [11] (Figure 1).

As the TFs identified in this study bind mtDNA in human cells at specific sites, we assessed their mitochondrial localization.