Sentence examples for bind at distinct sites from inspiring English sources

Chemical shift perturbation analysis, Ala mutagenesis, and isothermal titration calorimetry have been used to show that H3K4me3 and CYP33 RRM bind at distinct sites on PHD3.

For each channel, a CG system in which all four PIP2 molecules were bound to the channel at distinct sites was selected for conversion.

SPARC, also termed osteonectin, BM-40, and 43K protein, was initially identified by Termine et al. [ 6] as a bone-specific phosphoprotein that binds to collagen fibrils and hydroxyapatite at distinct sites.

The PHD3 domain binds H3K4me3 (preferentially) and the CYP33 RRM domain at distinct sites.

It has been proposed that the RelE2 corepressor of Streptococcus pneumoniae serves to bridge the antitoxin dimers bound at two distinct sites of the operator region, leading to greater avidity of binding of the TA complex when compared with the RelB2 alone (Chan et al. 2013).

These structures show TMC114 bound at two distinct sites, one in the active-site cavity and the second on the surface of one of the flexible flaps in the PR dimer.

Previous work has shown that oxysterols modulate Smoothened in an allosteric manner; that is, in contrast to several other known modulators of this protein, oxysterols bind at a distinct site (Nachtergaele et al., 2012).

On the basis of the significant structural differences between indolotryptolines and known V-ATPase inhibitors, it would not be surprising that they bind at a distinct site and therefore have selected for unique resistance-conferring mutations.

However, our results showed that both SGT1 and p23 bind to distinct sites of the HSP90.

The results suggest that GR is part of a larger complex bound to distinct sites at the vimentin/nestin filaments.

Also, it binds distinct sites at different domains in a single protein [ 28].