Your English writing platform
Discover LudwigSuggestions(1)
Similar(60)
The "cage convulsants," compounds with cyclical structure, bind at a convulsant binding pocket inside the GABAA ionophore at different and possibly overlapping positions.
Thus, RDX binds inside the chloride ionophore at a convulsant site overlapping with TBPS.
Homeward bound at a snail's pace.
To evaluate and quantify seizure susceptibility in Cdk5 KO mice, seizure latencies were scored after animals were treated with a convulsant, pilocarpine.
We show that knockdown of pk1a activity sensitizes zebrafish larva to a convulsant drug.
Thujone is a convulsant and binds to gamma-aminobutyric acid A (GABAA) receptors in the central nervous system.
The potency of RDX at the GABAA convulsant site (Ki of 21.1 μM) is similar to pentylenetetrazol, a convulsant commonly used in animal models of seizure and epilepsy that is also known to bind at the picrotoxin convulsant site (Coulter et al. 1990).
Having found that RDX binds to the convulsant site of the GABAA receptor, we next examined the functional consequences by determining the effect of RDX on GABAA receptor– mediated currents in the basolateral nucleus of the amygdala (BLA).
Pentylenetetrazole (PTZ) is a convulsant drug that induces general motor seizures in human and mouse (Velisek et al., 1992).
It's bound at the top with a spiral wire.
Not a single bound at all.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com