Sentence examples for bind and promote a from inspiring English sources

This difference was evident at the lower drug concentrations, supporting the notion that these drugs may efficiently bind and promote a beneficial conformational change of the VDR in keratinocytes.

MGP regulates BMP4 in vascular endothelial cells, and MGP is able to bind BMP2 and promote an association between BMP2 and matrix components; interaction between MGP and BMP2 interferes with binding of BMP2 to its receptor and activation of Smad1 [ 28, 31, 32].

Angiogenesis is initiated when endothelial cells are stimulated by specific molecules that bind to angiogenic receptors and promote a signaling cascade.

In a recent speech Gordon Brown sought to explore and promote a "golden thread" that binds diverse communities into a positive notion of nationhood.

In addition, N-cadherin ICD has been shown to bind and promote degradation of the transcription factor CREB binding protein [29].

APRIL can bind and promote tumor-cell proliferation of several cell lines that do not express detectable mRNA for TACI and BCMA[ 9, 64, 65].

These data suggest that prostate-cancer-associated mutations of SPOP abrogate its ability to bind and promote ubiquitination and degradation of AR.

The recombinant peptide was shown to mimic biological activity of native hepcidin as prior studies illustrated its ability to bind ferroportin causing its internalisation and promoting an increase in the levels of the LIP and a decrease in the expression levels of transferrin receptor 1 in macrophages [25].

Solanezumab is an antibody designed to bind to and promote the clearance of the β-amyloid protein, which forms plaques around the neurons of people with Alzheimer's.

This processivity requires a patch of backside residues that cooperate to bind Ub and promote multimerization of the Ub-charged enzyme.

NETs bind to and promote the killing of bacteria, fungi and Leishmania parasites when they are released into local tissue or the circulation.