Sentence examples for bind and become activated from inspiring English sources

The telomere-length phenotype of the double mutants could perhaps best be explained if Mre11/Tel1 complex bind and become activated at blunt telomeres or telomeres with short telomeric ssDNA regions, when Cdc13, Stn1 and Ten1 bind the G-rich ssDNA.

To achieve this, T cell needs to internalize peripheral T cell receptors not engaged by the antigen and then deliver them to the immunological synapse, where they can bind the antigen and become activated.

In the future it will be important to undertake binding studies and activation assays to determine whether mutation of these residues disrupts the ability of ubiquitinPhospho−Ser65 to bind to Parkin and become activated by PINK1.

Receptor (R) binds ligand (L) and becomes activated (RL).

Tyk2 is a Janus-family tyrosine kinase that is bound to cytokine receptors and becomes activated after ligand binding.

Caspase 8 is then bound to the DISC and becomes activated for executing apoptosis at both the mitochondrial and nuclear levels.

Our simulations are consistent with a nucleator that is inactive in solution and becomes activated when it binds to a MT (Figure 4B, top panels).

Upon activation of VEGFR2 by VEGF, VEGFR2 binds to dimeric PDCD10, translocates to the membrane, and becomes activated.

The functional form of the activation appears as a consequence of particular properties of this system: each transcription site can be occupied by up to four monomers and becomes activated when a tetramer is bound.

It would be highly interesting to evaluate whether RAGE can directly bind to, become activated, and mount a first immune reaction after ligation with specific PAMPs.

This co-operation between the three families of transcription factors is consistent with the fact that binding sites for Six4 and Mef2d are enriched at MRF bound genes that become activated during myogenesis (Blais et al, 2005).