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Our finding that the chemokine appears to bind and be transported on the filopodium, followed by internalization, is consistent with the idea that filopodia function in Cxcl12a uptake and in increasing the surface relevant for this action at the cell front.
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Unlike the cytoplasmic oxidative activation described above, GR must be reduced to bind ligand and be transported into nuclei.
The observed fluorescence quenching indicates that these compounds could efficiently bind with BSA and be transported to the target site.
Alternatively, in organs with discontinuous endothelium, immune complexes will bind to the fenestrae and be transported into the tissue.
It is possible this steroid hormone could be delivered to cells bound to a RBP7-TTR complex and be transported through the cell membrane by FABP4.
E. coli secretes the enterobactin siderophore (MW, 670 Da) into the media, where it binds iron, and is transported back into the cell.
Mn3+ binds to and is transported by transferrin (Aschner et al. 2007), whereas it is postulated that Mn2+ must use other transporter systems to enter cells (Takeda 2003).
Although complement containing ICs usually bind to erythrocytes and are transported to the liver for clearance, in plasma derived from anti-CCP+ RA patients we found circulating C1q-bound ICs that contain fibrinogen.
In genomic mechanism, 1 α,25(OH)2D3 binds to VDR and is transported to the nucleus [ 35].
Oxygen binds with hemoglobin and is transported in the form of oxyhemoglobin.
Vitamin D (D2 or D3) is absorbed in the gastrointestinal tract, binds to chylomicrons, and is transported via lymphatic system to blood circulation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com