Sentence examples for bind and be internalized from inspiring English sources
The ability of CPMV to bind and be internalized by several populations of APCs was characterized in vitro.
The coated Ad particles were found to bind to and be internalized by cells.
The synthesized Arg-Eu-HAP could effectively bind DNA without any cytotoxicity and be internalized into the cytoplasm and perinuclear of human lung epithelial cells.
In vitro exendin-3 specifically bound and was internalized by GLP-1R-positive cells.
Insulin molecules from the space of Disse can be bound and are internalized together with the receptor.
For example, McNamara et al (2006) have shown that an aptamer which binds and is internalized by prostate cancer cells via the prostate specific membrane antigen (PSMA) receptor achieves intratumoural delivery of siRNAs and inhibition of tumour growth in a mouse xenograft.
The new model element – the moving boundary of the synapse – is employed to incorporate the other effects that the structural dynamics of the TC has on the TCR distribution: the absorption of more membrane with the receptors into the synapse region, where the receptors bind ligand and are internalized at the high induced rate.
Clinically, the degree by which LDL particles bind to and are internalized by LDL receptors may be somewhat dependent upon the LDL particle oxidation.
While CPPs represent a promising class of siRNA carriers that rapidly penetrates the cell membrane, they lack receptor specificity; they bind to and are internalized by cells via heparan sulfates and other glycosaminoglycans in nearly all cell types in vitro and in vivo.
While the nine arginines bound siRNAs targeting the Japanese encephalitis virus, the rabies peptide selectively binds to and is internalized by the acetylcholine receptor, resulting in retrograde transport of the siRNAs in neuronal axons and protection from the lethal viral infection (Kumar et al, 2007).
After intravenous injection, scVEGF/99mTc preferentially binds to and is internalized by VEGFRs expressed within tumor vasculature, providing information on prevalence of functionally active receptors.
