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Reason can only recognize them as already there, and can bind agents only with the help of inclination or interest.
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While specific immunoglobulins and complement may enhance antibacterial activity of β-lactams, albumin may limitate its activity in highly bound agents.
Threading intercalators are high affinity DNA binding agents that bind by inserting a chromophore into the duplex and locating one group in each groove.
Open image in new window Fig. 2 Binding agent and biomass ratio.
They also bind cytotoxic agents, such as alkylating agents and confer resistance to these anticancer drugs.
We hypothesized that a biomimetic collagen hydroxyapatite (CHA) scaffold would bind both agents and produce superior in vivo outcomes.
Biorecognition layers formed by the phage-derived probes bind biological agents with high affinity and specificity and generate detectable signals in analytical platforms.
The design of novel biosensors for the detection of biological threats, such as Pseudomonas aeruginosa, requires probes that specifically bind biological agents and insure their immediate and efficient recognition.
Besides being essential to hemostasis, blood platelets have been recently shown to be able to bind infectious agents or engulf them.
Further, hSA has been shown to covalently bind OP agents in vitro [ 20, 21] and in vivo, and therefore OP bound to hSA may serve as a biomarker of OP exposure in humans [ 22].
An active function of platelets in inflammation has recently been demonstrated: several studies suggest that platelets serve as circulating sentinels that bind infectious agents and present them to the reticuloendothelial system [ 3- 5].
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