Sentence examples for bind a broad range from inspiring English sources

Such a T cell helper peptide must be promiscuous in its ability to bind a broad range of MHC class II alleles due to broad allelic variation in the human population.

The role of CD36 in these processes is attributed to its ability to bind a broad range of ligands [5].

p21Cip1 can bind a broad range of cyclin-CDK complexes, with a preference for those containing CDK2 (reviewed in [31], [45], and during a normal cell cycle, facilitates active cyclin-CDK complex formation to promote cell proliferation.

The protein has been proposed to serve multiple functions, including endocytosis of various immunoglobulins [ 25] and mediation of L-selectin-dependent lymphocyte rolling [ 26], and has been shown to bind a broad range of polar lipids [ 27].

Because it contains 310 helices region located between the C and E strands of D1 and a hydrophobic core consisting of the helices and C and E strands, LILRA3 D1 can binds a broad range of classical and non-classical HLAIs.

It was previously reported [20], [32] that LILRB2 binds a broad range of classical HLAIs HLA-A*1101 HLA-A*1101 -C*0401, and -Cw*0702) with andinities (Kd) ranging from ∼14 to ∼45 µM and also binds a non-classical HLA (HLA-G1) with affinitiesffinity (Kd≈5 µM).

D6 on the other hand, binds a broad range of CC chemokines including most agonists of CCR1, CCR2 and CCR5 (Bonecchi et al, 2004).

D6, an important member of the decoy receptor family, binds a broad range of CCR1, CCR2, and CCR5 ligands, prevents excessive infiltration of classical monocytes and neutrophils into the myocardium in a mouse model of myocardial infarction (Cochain et al, 2012).

We focused our attention on the upregulation of the HtrA1 gene, because its protein product binds a broad range of transforming growth factor (Tgf)- β family proteins (e.g., BMP4, BMP2 and Tgf- β1), which have critical roles in neurogenesis modulating either cell proliferation or cell survival.

Synthetic small molecules like the kind C4 seeks to develop, which involve linking synthetic molecules together, should be able to bind with a broad range of biological structures, and have a long-lasting effect.

It is well known that LILRB1 and LILRB2 bind to a broad range of classical and non-classical HLAIs [13], [14], [15] and major histocompatibility complex (MHC) class I-like molecules, such as UL18 [16].