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Our results suggest that binary modifications can play an important role in modulating the effects of specific histone modifications at different stages of development.
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With introduction of search area A and the continuous values assignments, the optimization problem of filter mask M is successfully converted from the binary values modification of the mask (belong or not belong) to continuous values m j modification.
The results of this analysis revealed an unexpected correlation between the presence of visible heterochromatin and the binary K9me3/S10ph modification on histone H3.
Subsequently, we defined a modification vector as the vector with binary scores of modifications at each position.
Fischle, W., Wang, Y. & Allis, C.D. Binary switches and modification cassettes in histone biology and beyond.
Fischle, W., Wang, Y. M. & Allis, C. D. Binary switches and modification cassettes in histone biology and beyond.
The model PC-SAFT is revised for binary interaction parameters modification, and the revised model is verified based on practical process design data.
We found a binary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylated for H3 and H4 and hypermethylated at Lys 4 and Lys 79 of H3, and inactive genes being hypomethylated and deacetylated at the same residues.
In order to make prediction of HPTFs based on histone modification dynamics, we made binary partition of all TFs' histone modification variation scores (i.e., combining histone modification variation scores "0" and "1 " into "Low_V," "2" and "3" into "High_V").
The modification of binary catalysts with gold led to increase the activity in the case of systems containing Co and Cu, and led to maintain the activity in the case of Ni-containing catalysts.
Moreover, even the conventional integrity checks can be fooled by a replaced binary code or minimized modification.
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