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To establish a more logical approach to repositioning a known drug to a new indication, we established a knowledge platform comprising binary linkages between diseases, drugs, and proteins, from which new and previously unknown connections can be drawn between drugs and diseases of interest.
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Conventional graph mining approaches are best suited for binary edges, where the structure of graph objects is deterministic, and the binary edges represent the presence of linkages between the nodes [2].
A posteriori binary cluster analyses (linkage between groups, phi-4-point correlation) were calculated to facilitate the categorization of these MiL areas.
More north-south and south-south linkages between research organisations and the private sector can help.
Close and defining linkages between politics and economics are likely to persist in 2013.
Consider the social, economic, and geographic linkages between Boston and New York, or New York and New Jersey and Connecticut.
@SEIresearch Aaron works on climate policy and financ, energy issues, and the linkages between the climate and development agendas.
"The linkages between the productivity and inequality challenges are still to be fully explored," it said in a paper.
"We need to know more about the linkages between the Chinese military, Chinese government and Chinese industry," Mr. Mulvenon said.
But, it said, there needed to be more research on the linkages between financial firms before this could happen.
Rail linkages between the cities flourish.
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