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Furthermore, we show that during transition from specification to differentiation in wild type endo16 expression profile, SLM reveals three binary activities are not sufficient to explain the transcriptional regulation of endo16 expression and additional activities of binding sites are required.
This conflict (one-to-many correspondence for the chosen state transition) suggests that the binary activities of the three cis-acting sites, UI, R and Otx are not enough to understand state transition activity at 50 61 pfh in the wild type expression profile and additional cis-acting sites are required in sequential logic modeling.
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Although HTS results provided complete dose response data, we used only binary activity summary data (i.e., actives or inactives) because of the binary nature of the CPDB data (i.e., carcinogenic or not carcinogenic).
The ab6A ORN shows a somewhat broader selectivity characteristic: activators are not as easy to discriminate from non-activators as for the other ORNs, and our method of assigning binary activity values may not have been appropriate in this case.
Investing is a binary activity, and its practitioners are speed junkies.
Figure 1 Proposed system: initially, kurtosis-based processing provides the binary Activity Area.
We use categorical binary activity results of 1354 drugs on 1596 protein targets.
For this paper, we consider only binary activity: the stream is either silent (G s)=0) or never satisfied (G s)=∞).
This preprocessing step transforms an integer frame to an image consisting of binary activity labels, thus significantly reducing the required storage space.
We computed the within-pair tetrachoric correlations and 95% confidence intervals for each binary activity measure separately in monozygotic (MZ) and dizygotic (DZ) twins.
BNs can be used to represent the binary activity of molecular species across cell populations (in vitro and in vivo).
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