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Individual probes were classified according to their GC content and matched to the corresponding GC bin controls.
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None of the GC bin control probes align to the D. melanogaster or D. simulans reference genomes.
A GC bin control is a standard Affymetrix control based upon the number of G/C bases (from 3 to 24) in the 25 mer probe.
GC bin control probes provide an estimate of nonspecific hybridization (Affymetrix 2005) and help to assess the overall quality of the hybridization.
Generating equal-read instead of "equal-size" genomic bins controls for read mappability so that each bin receives the same number of mappable positions, and hence similar read counts from each bin are expected from low-coverage WGS.
In one of these bins, controlling for expression levels results in more than a two-fold improvement in the p-value of the correlation.
The Salafi movement, which helped spawn Osama bin Laden, controls the towering mosque of Ibn Toubal.
Bin Laden controls "too much money to simply hide it under a mattress," says Mark Pieth, a professor of criminal law at Basle University in Switzerland and chairman of the OECD working group on bribery.
As defense minister, M.B.S. controlled the Army; as interior minister, bin Nayef controlled the country's vast internal security forces.
Tora Bora seemed to be an impregnable fortress when Osama bin Laden controlled the high ground.
In this work, we propose to use the short-time CDR (widehat {Gamma }_{tk}) estimated from the microphone signals at each TF bin to control the concentration parameter.
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