Exact(1)
Here, we review in a unifying manner several theories that describe the fluctuations (i.e. undulations) of bilayer shapes as well as their local coupling with lipid or protein density variation.
Similar(58)
This leads to a number of interesting experimental phenomena regarding bilayer shape dynamics.
However, the dynamics of bilayer shape transitions, especially their modulation by membrane proteins, and the resulting shape instabilities, are still not well understood.
For PG, PS, PC, PI and PE, the unsaturation index is known to play a pivotal role in defining whether each of these glycerophospholipid species acquires the bilayer forming shape of a cylinder or it attains the non-bilayer forming shape, either that of a cone or an inverted cone [ 18, 73, 74].
We find that the GdN clusters are coherently embedded in the GaN lattice, and have a bilayer platelet shape whose internal crystal structure is slightly distorted rocksalt.
For the IMM, a rise in the relative levels of glycerophospholipids having the bilayer forming shape of a cylinder reduces the extent of membrane curving [ 18, 73, 74].
Based on our data on mass spectrometric identification and quantitation of mitochondrial membrane glycerophospholipids, we calculated the relative levels of their species having the non-bilayer forming shape of a cone or an inverted cone as well as the relative levels of glycerophospholipid species exhibiting the bilayer forming shape of a cylinder.
The formation of mitochondrial cristae by the IMM domains having positive curvature (i.e., membrane curving towards the mitochondrial matrix) is known to require both glycerophospholipids having the non-bilayer forming shape of a cone and glycerophospholipids exhibiting the non-bilayer forming shape of an inverted cone [ 18, 73, 74].
Microelectrophoresis of liposomes, changes in boundary potential of planar bilayers, the shape of compression curves and potentials of lipid and lipid/peptide monolayers were used to monitor the electrostatic factors in polymer adsorption to the membrane and peptide polymer interactions.
On note, PA, CL and MLCL are known to be always present in the non-bilayer forming shape of a cone, regardless of their unsaturation indexes [ 18, 73].
Furthermore, F-BAR domains (a subtype of BAR domains) assembled on membrane bilayers form a polymeric coat [12] that likely supports the tubular shape of the membrane.
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