Sentence examples for bilayer conformation from inspiring English sources

If model membranes can only accommodate 2 3% TGLs in the canonical bilayer conformation, and even less so if cholesterol is present [21], and more than 6 7% TGLs is indeed present in the membranes of cholesterol-containing living cells, where does the excess TGL go?

For instance it has been instrumental to unravel the bilayer conformation of the fusion peptide of the influenza virus hemagglutinin [ 75].

We therefore hypothesized that LCA may (i) reduce the abundance of the IMM domains displaying negative curvature characteristic of mitochondrial contact sites between the IMM and OMM; (ii) decrease the abundance of the IMM domains exhibiting positive curvature typical of mitochondrial cristae formed by the IMM; and (iii) increase the abundance of the IMM domains having flat bilayer conformation.

Moreover, it is plausible that the observed in yeast grown in the presence of exogenous LCA build-up within the mitochondrial matrix of cristae disconnected from the IMM and thus exhibiting flat bilayer conformation was caused by the substantial rise in the relative levels of bilayer forming (i.e., cylinder-shaped) mitochondrial glycerophospholipids seen in these cells.

Crystal structures of β-barrel pore forming toxins like 〈 hemolysin and aerolysin have demonstrated that residues lining the trans leaflet of the bilayer in a rivet conformation must be hydrophobic in order to efficiently promote membrane insertion [12], [13].

In particular, for proteins containing transmembrane segements, S-palmitoylation is suggested to change the tilt of the transmembrane segments within the bilayer or alter its conformation, thereby promoting protein protein interaction and complex formation.

To test whether the substrate-coupled ATP turnover cycle in lipid bilayers involves the conformations identified in detergent micelles, we determined distance distributions in the NBD and TMD pairs following reconstitution of BmrCD double mutants in nanodiscs of PC/PA.

Here, using EPR spectroscopy, we show that the isolated VSD of KvAP can remain monomeric in a reconstituted bilayer and retain a transmembrane conformation.

When from DA subphase without UV light, films with small aggregates on surface dominate with the main height distribution of 3.4 ± 0.3 nm (Fig. 3b'), suggesting the possible interfacial adsorption of DA molecules on GO sheet due to hydrophilic force and Van der Waals force or bilayer film formation due to conformation change of GO-SH.

If true, then the equilibrium conformation of the bilayer would be different in the presence of protein.

In this context, it should be noted that recent coaxial confocal-AFM imaging and FRET assays [114] suggest that saposin C may perturb membrane bilayers by adopting an open conformation, thereby exposing its inner hydrophobic surfaces for interactions with lipid acyl chains.