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As President Obama said at a press conference in October, "one of the biggest problems about the collapse of Lehman [Brothers] and the subsequent financial crisis and the whole subprime lending fiasco is that a lot of that stuff wasn't necessarily illegal, it was just immoral or inappropriate or reckless".
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Sometimes the biggest problem about writing this newsletter is coming up with a title.
And that is really probably the biggest problem about [Scottish Futures Trust] activities – the lack of information we have, the lack of accountability," Jim Cuthbert said.
Which illustrates perhaps the biggest problem about the Supreme Court's ruling: its potential to create wasteful litigation about whether or not the bankruptcy court can enter a final order in a particular matter.
If the changes involved were understood, picking the right size and composition of nanoparticle would be less a matter of guesswork.The biggest problem about moving from laboratory to industry, though, is the question of scale.
Many people have complained that the biggest problem about AirPods is that the buds slip out of their ears too easily, and many more who haven't experienced this, are none the less worried it could happen.
"We live in a democracy and believe the free exchange of ideas is crucial to critical thinking," Baltzell said, adding that the biggest problem about the bill is that the language is so broad.
Just days after The New York Times reporter Barry Meier's book A World of Hurt: Fixing Pain Medicine's Biggest Problem (about the over-prescription of OxyContin) the e-book single rocketed to become the industry's best-selling e-book single.
Bubbling under, however, are bigger problems about the quality and cost of childcare.
"One of the big problems about gay information is that it does not get through firewalls," adds Ms Hunt.
As a boy, he says, he conceived the idea that he would be a biophysicist, even though he didn't really know what that meant, because, as he puts it, "I wanted to solve a big problem about life".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com