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Hence, delivery of therapeutic peptides and proteins to the central nervous system is the biggest challenge for development of more effective neuropharmaceuticals [ 307].
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Thus, one of the biggest challenges for development of a vaccine against VL is to unravel the prechallenge predictor for vaccine success.
Safe medication prescribing presents the biggest challenge for the development of an EMR suitable for use in resource-limited settings.
Western dominance is the one of the biggest challenges for developing nations, says Alice Munyua, a researcher and policy development expert, representing Kenya and Africa on forums such as Icann.
One of the biggest challenges for the development of a Ge metal-oxide semiconductor (metal-oxide semiconductord appropriate passivating MOSerials and metechnologys for the Ge/hish-k intorfinds.
This suggests that the biggest challenge for associations wishing to fund development will be cost control.
The biggest challenge for the company, its founders and development experts say, is accountability.
However its low antigenicity and immunogenicity, which are related to its small size, poses a big challenge for vaccine development.
Identifying innovative solutions, both managerial and related with a possible integration with other sustainable mobility, is a big challenge for local development policy.
To further increase the imaging speed while maintaining the system axial resolution at less than 10 μm, the acceptable performances, e.g., system sensitivity rolling off and detectable depth range, are still a big challenge for the development of retinal SDOCT system.
We are also focusing on product development, because besides a shortage of funding, the development of resistance is the biggest challenge for tackling malaria.
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