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The ideal cutoff of the OAAT for the screening of OSA (AHI ≥ 5) as the bigger specificity value has been also detected, among the ones with a 100% sensitivity value.
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Winthrop described the core of that mission with great specificity.
But with our ROC curves, improvements in sensitivity implied big reductions in specificity, and the overall efficacy was quite better using Youden's index to select the cutoff points (Tables 5 and 6).
Prenuptial agreements have grown in specificity.
Compared to the two-residue insertion (Tyr Gly) in SmCL2, the three-residue insertion appeared in PwCP5 may bring bigger difference in substrate specificity between PwCP1 4 (cruzipain) and PwCP5 (cathepsin L-like).
The results suggested that read length (RL) also has a big impact on mapping specificity (Table S3).
The power of the method lies in the use of short peptide motifs which on one hand are big enough to provide specificity and on the other hand, small enough to cover a broad spectrum of proteins and most importantly the use of physiologically relevant filters namely, accessibility in terms of folded structure of a protein and subcellular localization.
A cutoff value for best discrimination between patients of high and low risk for development of citrate accumulation was assessed using the Youden Index, so from all observed values the one giving the biggest sum of sensitivity and specificity is described as the best cutoff value.
An even greater specificity informs the big-screen adaptation of Kevin Sampson's Wirral-set novel Awaydays, which concerned aspiring Tranmere Rovers hooligan/arty post-punk music fan Carty and his closeted gay pal Elvis, ricocheting between the ruck and Echo & the Bunnymen gigs in 1979-80.
As in Guttmann et al. study [ 4], where the biggest sum of sensitivity and specificity was for 3 claims, it was set at 3 deliveries per year to limit prescription errors.
Although her role isn't much more than a cameo, she gives it such pungent specificity that it feels bigger.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com