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However, the downing of a U-2 over the Soviet Union in 1960 and the capture of its pilot exposed the covert flights, and represented one of the bigger setbacks of the Eisenhower administration, helping to derail the president's initiative for détente with Moscow.
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The previous year had been an even bigger setback.
The elections were an even bigger setback for her coalition partner, the Free Democrats (FDP).
An even bigger setback for McCain followed when networks projected Ohio would go to Obama.
But there have been big setbacks.
It enjoyed great commercial success, but not without one or two big setbacks.
Burns said British comedy had suffered two big setbacks in the last year.
Together this represents one of the biggest setbacks to social mobility in modern times.
The reaction Wednesday was swift and painful, with stock markets around the world suffering their biggest setbacks since June.
There is no arguing that the Democrats have suffered a series of big setbacks at the local level.
One of the biggest setbacks for queer liberation in the UK this year was the election of a Conservative government, committed to an extensive austerity agenda.
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CEO of Professional Science Editing for Scientists @ prosciediting.com