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For this reasons, when working with big sets of genes, it would be more probable that they will be enriched for more generic GO terms (higher in the graph structure).
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Indeed, if the combination of clinical factors and a small number of biomarkers would suffice to either (i) improve the prognostic prediction or (ii) reduce the number of biomarkers while performing as good as when using a bigger set of genes alone, this would imply major cost cutting in biomarkers driven clinical treatments.
"It's about a big set of ideas.
The first big set of transcripts (1004 zebra finch sequences) was present in seven bird species.
She gave us a big set of dishware.
I anticipate that more accurate models and the analyses of bigger sets of microRNA target sites will shed light on how microRNA function diversify and, more generally, how gene regulation evolves.
Interestingly, more than 50% of bladder cancer patients harbor genetic aberrations in a bigger set of chromatin remodeling genes including UTX, CREBBP, EP300, ARID1A, CHD6, MLL1, MLL3, and NCOR1.
It was a big surprise that a complex behaviour like courtship is regulated by a few sets of genes [1, 2], and it is strongly believed that these genes interact with cascades of downstream genes that regulate individual parts of the behaviour.
They compared the big-picture genetic profiles of 26 first-time meditators to 26 experienced meditators and found that different sets of genes were expressed.
But they can equally well be seen as showing the competing influences of two genes or sets of genes.
But more importantly, they found 1,768 new gene families — sets of genes that share a common ancestor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com