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"The big obstacles for people who want to buy are saving enough for a down payment and qualifying for a mortgage, because credit is still tight," Mr. Kolko said, saying that the Fed program would not directly address those problems.
Limitation in sample quality and quantity is one of the big obstacles for applying metatranscriptomic technologies to explore gene expression and functionality of microbial communities in natural environments.
Ehrhardt also noticed that recruitment and personal development are two big obstacles for companies trying to develop and express their own culture.
The big obstacles for Brigade are proving that publicly stating your political opinions is both something you actually want to do, and that you want to do on its app.
According to the analysis of district leaders, poor management skills of commune leaders create big obstacles for the socio-economic development in general and child development in particular.
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"A big obstacle for him is being afraid to go back.
Alex Hales remains the big obstacle for Warwickshire, on 139 from 225 balls so far, writes Brian Halford.
The sheer number of applications written for Apple and Android is a big obstacle for the new contenders.
The big obstacle for a European club looking to sign a locked-out N.H.L. star is the cost of insuring that player against injury.
This, it seems, has far more to do with complacency than outright hostility, but indifference is a big obstacle for black British comics.
Michelle Kwan created a big obstacle for herself yesterday at the World Figure Skating Championships in Nagano, Japan, when she stumbled out of a combination jump in the short program and landed in third place.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com