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In our previous method [12], the major cluster from which the centroid to be used as model was determined by finding the cluster with the biggest number of samples in it.
This is a preliminary data study and a bigger number of samples are needed for our study.
Findings based on analyzing a small number of deeply profiled DNA methylomes (i.e., a discovery panel) can then be validated using array-based approaches, which can be applied to a much bigger number of samples (i.e., a validation panel).
The cluster sizes range from almost only individual particles (sample# 1) to bigger number of NPs (sample# 2, sample# 3, and sample# 4).
After stabilization, at pH 5.2, the amount of released drug is bigger for a bigger number of bilayers: samples with eight bilayers release 1.32 times more drug than five bilayer samples and 1.63 times more than two bilayer samples.
I tried a sample Houston-to-Seattle round trip and got 1,100 price and schedule options (variable connections account for the big number of choices).
A big number of our patients needed ventilator support.
Our analysis identified a big number of H3-like genes.
That's a very big number of patients.
The strengths of this study are the large sample size, comprehensive assessment and bigger number of controls than the original ABCS 135 validation paper.
Biggest number of immunopositive nuclei in comparison to the others.
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