The big issue for me concerns isolationism and the rise of rightwing extremism in Europe and beyond.
It deflected attention from climate change, another big issue of concern.
Forests have long been a big issue of concern in Cambodia and across south east Asia.
Mr Hemming, MP for Birmingham Yardley, said the move had not been debated enough in Parliament, adding: "It's a big issue for parents and my concern is that they haven't been heard".
In the past decade, copyright law has been a big issue for retailers; mostly, it concerns luxury brands battling street merchants.
The third big issue for the Luxembourg gathering concerned the ExoMars rover, which is due to be sent to the Red Planet in 2018 to search for signs of past or present life.
The plot was "not confined to this country, not confined to the firms we have heard about, and it's a big issue for the public to be concerned about, but the fact is it was discovered by accident and only emerged as a problem because of your activity", the judge, Owen Davies QC, told the men as he passed sentence on Monday.
"The environmental concerns are not a big issue for us," he said, because the alternatives are far too expensive.
It is still a big issue for introduction of exogenous genes by virus in clinical translation due to safety concern including tumorigenesis.
(This is a big issue for the United States, which has not recognized the rebels, at least in part out of concern over who its leaders really are).
Confidence is a big issue for Huffman.
